Region 1 - Northwest
- IU 5 (Northwest Tri-Co. IU) Crawford, Erie and Warren counties
- IU 6 (Riverview IU) Clarion, Forest, Jefferson and Venango counties and DuBois SD in Clearfield Co.
Region 2 - Midwest
- IU 4 (Midwestern IU) Butler, Lawrence and Mercer counties
- IU 27 (Beaver Valley IU) Beaver Co.
- IU 28 (ARIN IU) Armstrong and Indiana counties
Region 3 - Southwestern
- IU 1 (Intermediate Unit 1) Fayette, Greene and Washington counties
- IU 7 (Westmoreland IU) Westmoreland Co.
Region 4 - North Central
- IU 9 (Seneca Highlands IU) Cameron, Elk, McKean and Potter counties
- IU 10 (Central IU) Centre, Clearfield and Clinton counties (except DuBois SD in Clearfield Co.)
Region 5 - Central Heartland
- IU 8 (Appalachia) Bedford, Blair, Cambria and Somerset counties
- IU 11 (Tuscarora IU) Fulton, Huntingdon, Juniata and Mifflin counties
Region 6 - Susquehanna River
- IU 15 (Capital Area IU) Cumberland, Dauphin and Perry counties, and Northern York SD in York Co.
- IU 16 (Central Susquehanna IU) Columbia, Montour, Northumberland, Snyder and Union counties
Region 7 - Northeast
- IU 18 (Luzerne IU) Luzerne Co. and Tunkhannock SD in Wyoming Co.
- IU 19 (Northeastern Educational IU) Lackawanna, Susquehanna and Wayne counties, and Lackawanna Trail SD in Wyoming Co.
Region 8 - Mid East
- IU 14 (Berks Co. IU) Berks Co.
- IU 20 (Colonial Northampton IU) Monroe, Northampton and Pike counties
- IU 21 (Carbon-Lehigh IU) Carbon and Lehigh counties
- IU 29 (Schuylkill IU) Schuylkill Co.
Region 9 - South Central
- IU 12 (Lincoln IU) Adams, Franklin and York counties (except Northern York SD in York Co.)
- IU 13 (Lancaster-Lebanon IU) Lancaster and Lebanon counties
Region 10 - Philadelphia
- IU 26 (Philadelphia IU) SD of Philadelphia
Region 11 - Buxmont
- IU 22 (Bucks Co. IU) Bucks Co.
- IU 23 (Montgomery Co. IU) Montgomery Co.
Region 12 - Endless Mountains
- IU 17 (BLaST IU) Bradford, Lycoming, Sullivan and Tioga counties
Region 13 - Pittsburgh
- IU 2 (Pittsburgh-Mt. Oliver IU) Pittsburgh Public Schools
Region 14 - Allegheny
- IU 3 (Allegheny IU) Allegheny Co.
Region 15 - Penns Grant
- IU 24 (Chester Co. IU) Chester Co.
- IU 25 (Delaware Co. IU) Delaware Co.